Prof. Micha Fridman

The Fridman laboratory is engaged in the use of organic chemistry, especially carbohydrate chemistry, to solve key biological and medicinal problems. Our interdisciplinary studies involve the use of organic chemistry, microbiology, cell biology, molecular biology, and confocal microscopy to study and/or alter the mode of action of biologically active molecules with the focus on novel approaches for the development of antimicrobial and antitumor agents. Our current research covers four major topics: I) rational design of membrane targeting antibiotics, II) development of chemoenzymatic and chemical approaches to circumvent the action of certain resistance mechanisms to aminoglycoside antibiotics, II) structure-function studies and rational design of novel antitumor agents, and IV) exploration of bacterial biofilm matrix assembly and strategies for its formation inhibition.

• B.A. in Molecular Biochemistry, Technion, Israel, 1997-2000

• M.Sc. in Organic Chemistry, Technion, Israel, 2000-2001

• Direct pathway to Ph.D. studies, Department of Chemistry, Technion- Israel Institute of Technology, 2002-2005

• Post-Doctoral Research Fellow, Department of Chemistry and Chemical Biology, Harvard University, 2005-2008

• Senior lecturer, School of Chemistry; Faculty of Exact Sciences Tel Aviv University, Israel, 2008-Present

• Miriam and Aaron Gutwirth Award for Excellence during M.Sc. Studies, 2001

• Wolff Foundation Award for Excellence during Ph.D. studies, 2004

• Israel Chemical Society Award for excellence of Ph.D. research students, 2005

• Rothschild Foundation Post-Doctoral Fellowship, 2005